Semaglutide

Note: This is general medication information. Prescription, dosage, and suitability depend on individual health, so any medication decisions should be made with your treating physician who knows your full history.
Drug classGLP-1 Receptor Agonist
Brand namesOzempic, Wegovy, Rybelsus, Semanat, Obeda, Semaglyn, Semasize, Zidusema
Prescription Required
Price (India)Rs. 325 to Rs. 2,025 per weekly injection (0.25mg starter dose)

Semaglutide is a GLP-1 receptor agonist used for type 2 diabetes management and chronic weight management. After the March 2026 patent expiry in India, eight CDSCO-approved manufacturers launched generic versions, dramatically reducing costs.

How it works

Semaglutide mimics the action of GLP-1, a naturally occurring hormone released after eating. It slows gastric emptying, increases insulin secretion in response to meals, and signals fullness to the brain.

Available brands in India (2026)

Branded original: Ozempic by Novo Nordisk (~Rs. 2,025 per weekly injection). Generic options range from Rs. 325 (Natco Semanat vial) to Rs. 510 (Sun Pharma Semaglyn pen).

Typical dose schedule

Week 1-4: 0.25mg weekly. Week 5-8: 0.5mg weekly. Week 9+: Increase up to 1.0mg or 2.0mg based on response. Never start at higher doses.

DR
Written by

Dr. Rahul Tripathi

PhD Pharmaceutical Sciences · Pharmaceutical Reviewer

Dr. Rahul Tripathi is a pharmaceutical sciences PhD with 14+ years in drug development and clinical pharmacology, reviewing all medication-related content.

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DS
Medically reviewed by · April 24, 2026

Dr. Selva Bharti

MD Medicine, DM Cardiology · Medical Reviewer, Endocrinology and Internal Medicine

Dr. Selva Bharti is an internal medicine physician with specialized training in cardiology and endocrinology, reviewing diabetes, thyroid, PCOS, and cardiovascular content on MasterDoctor.

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